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Comptox MCP Server

Exposes EPA Computational Toxicology (CompTox) evidence federation through MCP, enabling chemical identity, hazard, exposure, and bioactivity data retrieval for AI agents.

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// key findings
No credential exfiltration, no sensitive file access, no obfuscation
Static analysis found nothing flowing your secrets to unexpected places.
Open source with a license and README
Anyone can audit the code, the license is declared, and the publisher documents what it does.
🔐
You'll be asked for 9 credentials: CTX_API_KEY, EPA_COMPTOX_API_KEY, ctx_x_api_key, MCP_EPACOMP_TOX_API_KEY, EPA_MCP_BEARER_TOKEN, EPACOMP_AD_DESCRIPTOR_BACKEND_BEARER_TOKEN, EPACOMP_AD_DESCRIPTOR_BACKEND_API_KEY, EPACOMP_AD_RULE_BACKEND_BEARER_TOKEN, EPACOMP_AD_RULE_BACKEND_API_KEY
These are read from process.env at runtime. Make sure you trust where they’ll be sent.
// required environment variables
This server reads these from process.env. You'll be asked to provide them before it can run.
🔐 secretCTX_API_KEYset in .env
🔐 secretEPA_COMPTOX_API_KEYImportant: The server needs a valid EPA CompTox API key. Set CTX_API_KEY (preferred) or in .env before starting the transport.
configCTX_HAZARD_HEALTH_URL
configCTX_EXPOSURE_HEALTH_URL
configCTX_BIOACTIVITY_HEALTH_URL
configENDPOINT_CHECK_TIMEOUT
configEPACOMP_SKIP_VENV_REEXEC
configctx_api_host
configCTX_API_BASE_URLOptional https://comptox.epa.gov/ctx-api Base URL for CompTox API.
🔐 secretctx_x_api_keyCTX_API_KEY ✅ – CompTox API key used for all downstream requests. Fallbacks: EPA_COMPTOX_API_KEY, .
configMCP_EPACOMP_TOX_SERVER_URL
🔐 secretMCP_EPACOMP_TOX_API_KEY
configCTX_CHEMICAL_HEALTH_URL
configEPA_MCP_HTTP_ENDPOINT
🔐 secretEPA_MCP_BEARER_TOKEN
configEPACOMP_TOX_VERSION
configTOXMCP_ENVIRONMENT
configEPACOMP_AD_EVALUATOR
configEPACOMP_AD_SIDECAR_TIMEOUT_SECONDS
configEPACOMP_AD_SIDECAR_FALLBACK_TO_DELEGATED
configEPACOMP_AD_DESCRIPTOR_BACKEND_URL
configEPACOMP_AD_DESCRIPTOR_BACKEND_TIMEOUT_SECONDS
🔐 secretEPACOMP_AD_DESCRIPTOR_BACKEND_BEARER_TOKEN
🔐 secretEPACOMP_AD_DESCRIPTOR_BACKEND_API_KEY
configEPACOMP_AD_RULE_BACKEND_URL
configEPACOMP_AD_RULE_BACKEND_TIMEOUT_SECONDS
🔐 secretEPACOMP_AD_RULE_BACKEND_BEARER_TOKEN
🔐 secretEPACOMP_AD_RULE_BACKEND_API_KEY
// full audit trail
The full breakdown of what we checked, the deductions that landed, the network hosts, the dependency advisories, and concrete fix guidance is available to verified publishers.
// improvement guidance — verified publishers only
We have 2 concrete improvements we can share with the publisher of this MCP. Each comes with specific guidance to raise the trust score.
// embed badge in your README
[![M8ven Score](https://m8ven.ai/badge/mcp/toxmcp-comptox-mcp-1f753y)](https://m8ven.ai/mcp/toxmcp-comptox-mcp-1f753y)
commit: ef2d0e80bf484e757c3bb9cd9504c8a3a983edda
code hash: 0c1bf7b01fe83e831d77636ce82625945905e8cd236f74491ecb1751f60fa204
verified: 6/18/2026, 10:54:00 AM
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Comptox MCP Server · M8ven Trust Score | M8ven